Author: Daniele Ramazzotti
Date: 2026-04-28

# Introduction

Daniele Ramazzotti, Fabrizio Angaroni, Davide Maspero, Alex Graudenxi, Luca De Sano and Gianluca Ascolani

#### April 28, 2026

#### Package

VERSO 1.22.0

## 0.1 Overview

VERSO is an algorithmic framework that processes variants profiles from viral samples, to produce phylogenetic models of viral evolution from clonal variants and to subsequently quantify the intra-host genomic diversity of samples. VERSO includes two separate and subsequent steps; in this repository we provide an R implementation of VERSO STEP 1.

## 0.2 Installing VERSO

The R version of VERSO can be installed from Bioconductor. To do so, we need to install the R packages VERSO depends on and the devtools package.

    if (!require("BiocManager", quietly = TRUE))
        install.packages("BiocManager")

    BiocManager::install("VERSO")

## 0.3 Debug

Please feel free to contact us if you have problems running our tool at daniele.ramazzotti1@gmail.com or d.maspero@campus.unimib.it.